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Combined metabolic intervention: The combination of CPS1 inhibitors and GLS inhibitors may simultaneously disrupt tumor ammonia detoxification barriers and alleviate ammonia toxicity in CD8 + T cells

doi: 10.1007/s12011-019-1637-6 6

Therefore, ATF4-mediated upregulation of SHMT2 contributes to a higher level of dTTP in T315I-Bcr-Abl-32D cells